Genital herpes transmission rates? (HSV-2 and HSV-1)

Let’s talk real numbers

When you first get diagnosed with herpes, the fear isn’t really about the virus itself, it’s about what it means for your relationships and your sex life going forward. Will you pass it to someone you love? Is safe sex even possible?

The short answer: yes, absolutely. And the numbers back that up. The transmission rates for herpes are genuinely lower than most people expect, and with a few straightforward precautions, you can reduce the risk even further.

The research cited throughout this article comes from three landmark studies on herpes transmission: Corey et al. (2004) in the New England Journal of Medicine, Cranston et al. (2016), and Wald et al. (2001) in JAMA. These are the gold-standard studies. (Download our free handouts for a printable summary of these stats you can share with a partner.)

HSV-2 annual transmission rates in couples

Most herpes transmission research follows “discordant couples”, that just means one partner has herpes and the other doesn’t. Researchers tracked real couples over time to measure how often the uninfected partner actually contracted herpes under different conditions.

Here are the annual transmission rates for HSV-2:

Protection used Female risk
(male partner has HSV-2)
Male risk
(female partner has HSV-2)
No protection ~10% per year ~4% per year
Condoms only ~5% per year ~2% per year
Antivirals only ~5% per year ~2% per year
Condoms + antivirals ≈2.5% per year ≈1% per year

Read those numbers again. Even with no protection at all, the annual risk is 4% for men and about 10% for women. That means in a full year of regular sex with an infected partner and zero precautions, there’s still a 90–96% chance it won’t be transmitted.

When you combine condoms with daily antiviral medication? The annual risk drops to about 1% for men and 2.5% for women. Those are remarkably low numbers, far lower than most people imagine when they hear “herpes.”

Why is the rate higher for women? It comes down to biology. The vaginal lining has more mucous membrane surface area than the penis, which gives the virus more opportunity to make contact. It’s not about who is “more at risk” in any moral sense, it’s simply anatomy.

One more thing about these annual rates: they tend to be highest in the first year or two after diagnosis. Over time, your immune system gets better at suppressing the virus, which means fewer outbreaks and less shedding. So if you’ve had herpes for several years, the actual transmission risk to your partner may be even lower than the numbers above suggest.

Per-act risk: What about a single encounter?

A lot of people want to know: “What are my chances from just one time?” This question comes up especially around casual encounters or the early stages of dating. The per-act numbers are even more reassuring:

Direction Per-act risk
(no protection)
Condom risk reduction
(per act)
Male-to-Female ~0.3% per act Up to 96% reduction
Female-to-Male ~0.04–0.10% per act ~65% reduction

So for a single sexual encounter with someone who has HSV-2, the per-act risk of male-to-female transmission without protection is roughly 0.3%, that’s about 3 in 1,000. Female-to-male is even lower, around 0.04–0.10% per encounter.

With condoms, male-to-female per-act transmission drops by up to 96%, and female-to-male drops by about 65% (Cranston 2016). These are per-act reductions, meaning each individual sexual encounter.

What about a one-night stand?

This is one of the most common questions: “What are the odds of getting herpes from a one-night stand?” The honest answer is that it depends on a lot of variables, whether the person has HSV-1 or HSV-2, whether they’re currently shedding, whether a condom is used, and whether they’re on antivirals.

But based on the per-act data above, a single protected encounter with someone who has HSV-2 carries a very low risk. If a condom is used and the person isn’t having an active outbreak, the per-act risk could be well under 0.1%. Of course, in a casual situation you may not know your partner’s status at all, which brings us back to the fact that condoms are always a good idea, herpes or not.

Low risk doesn’t mean zero risk. And these numbers assume no active outbreak is present. During an outbreak, transmission risk increases significantly because there’s so much more virus at the skin’s surface. That’s why avoiding sexual contact during outbreaks, and learning to recognize your prodrome symptoms, matters so much.

How condoms reduce herpes transmission

You may have heard the claim that “condoms don’t protect against herpes.” That’s a myth. Here’s the nuance:

A pooled analysis by Martin et al. (2009) in JAMA Internal Medicine found that consistent condom use reduces HSV-2 acquisition by about 30% overall. That number might sound modest at first, but when you break it down by direction, the picture is more striking:

  • Male-to-female (per act): condoms reduce transmission by up to 96%
  • Female-to-male (per act): condoms reduce transmission by about 65%

The reason condoms don’t eliminate the risk entirely is that herpes spreads through skin-to-skin contact, and condoms don’t cover all potentially affected areas (inner thighs, buttocks, the base of the penis). But they do cover the primary transmission zone, and the data clearly shows they make a significant difference.

The bottom line on condoms: use them. They help a lot more than the myth suggests.

How antivirals reduce herpes transmission

Daily antiviral medication (usually valacyclovir (Valtrex)) is another powerful tool. The landmark Corey et al. (2004) study in the New England Journal of Medicine showed that daily valacyclovir reduces HSV-2 transmission by 48%.

Antivirals work by suppressing viral replication, which means:

  • Fewer outbreaks (and milder ones when they do happen)
  • Less asymptomatic shedding, the virus being present on the skin without visible symptoms
  • A lower overall viral load on the skin’s surface

When you combine daily antivirals with consistent condom use and avoid sex during outbreaks, you get the strongest protection available, bringing the annual risk down to roughly 1–2.5% depending on direction.

Talk to your doctor about whether daily suppressive therapy makes sense for your situation. It’s not mandatory (plenty of people manage herpes just fine without it) but it’s a good option to have in your toolbox, especially when navigating a new relationship.

HSV-1 genital transmission: The oral sex factor

Here’s something that surprises a lot of people: over 50% of all new genital herpes cases are caused by HSV-1, transmitted through oral sex. That means someone with a cold sore (oral HSV-1) can pass it to a partner’s genitals during oral sex. (For the full breakdown of the two types, see our guide to HSV-1 vs. HSV-2.)

The good news? Genital HSV-1 tends to behave quite differently than genital HSV-2:

  • Fewer recurrences: typically 0–1 outbreaks per year after the first year (compared to an average of 4–6 for genital HSV-2)
  • Less shedding: the virus is active on the skin about 3–5% of days, versus ~10–15% for genital HSV-2
  • Lower transmission risk: the lower shedding rates strongly suggest a lower chance of passing it to a partner

The specific transmission data for genital HSV-1 is less robust than for HSV-2, because most of the large studies focused on HSV-2. But the significantly lower shedding frequency is a strong indicator of lower risk. For a deeper dive, read our article on genital HSV-1 and oral sex.

What about asymptomatic shedding?

One of the trickiest aspects of herpes is that it can be transmitted even when no sores are visible. This is called asymptomatic shedding, the virus travels to the skin’s surface without causing any symptoms you can see or feel.

How often does it happen?

  • Genital HSV-2: shedding occurs on roughly 10–15% of days
  • Genital HSV-1: shedding occurs on roughly 3–5% of days
  • Oral HSV-1: shedding occurs on roughly 6–9% of days

This is a big part of why herpes is so common globally, most transmission actually happens when people don’t even know the virus is active. But here’s the key insight: the viral load during asymptomatic shedding is much lower than during an active outbreak. Lower viral load = lower chance of transmission. This is also where daily antivirals really shine, because they significantly reduce the number of shedding days.

The full picture: Risk reduction at a glance

Here’s a summary of how each protective measure reduces transmission risk:

Protective measure Risk reduction Source
Condoms (overall annual) ~30% Martin 2009
Condoms, M→F (per act) Up to 96% Cranston 2016
Condoms, F→M (per act) ~65% Cranston 2016
Daily antivirals ~48% Corey 2004
Avoiding sex during outbreaks Eliminates highest-risk period -
All combined ≈1–2.5% annual risk Combined data

The biggest risk factor most people overlook

Here’s something that puts all of these numbers in perspective: roughly 80% of people with herpes don’t even know they have it. They’ve never been tested, never had a noticeable outbreak, and have no idea they’re carrying the virus.

That means the vast majority of herpes transmission happens from people who are completely unaware of their status. They’re not taking antivirals. They’re not watching for prodrome. They’re not avoiding sex during outbreaks because they don’t know they’re having outbreaks.

You, the person reading this, the person who knows their status, are already in a far better position to protect your partners than the 80% who have no idea. Your awareness is genuinely your superpower here. You can:

  • Recognize your prodrome symptoms and avoid contact when the virus is most active
  • Use condoms to reduce per-act risk by up to 96%
  • Take daily antivirals to reduce transmission by another 48%
  • Have honest conversations so your partner can make an informed choice

When you stack all of that together, the risk becomes remarkably small. You are not doomed to pass this to someone you care about. Far from it.

A note on herpes and pregnancy

If you’re thinking about starting a family, you may be wondering about the risk of passing herpes to a baby. The risk is almost entirely limited to active outbreaks during delivery. If a mother has a known history of herpes and no active outbreak at the time of labor, the risk of neonatal transmission is very low (under 1%). Doctors typically prescribe daily antivirals starting around 36 weeks to reduce the chance of an outbreak at delivery. If an outbreak is present during labor, a cesarean section is usually recommended. Talk to your OB/GYN, this is very manageable with proper medical care.

The bottom line

Herpes transmission rates are real, and they matter. But they’re also way lower than the shame and stigma would have you believe. The research shows that with a bit of awareness and some simple precautions, the risk of transmitting herpes to a partner is genuinely low.

You didn’t ask for this diagnosis. But you do get to decide what you do with it. And the fact that you’re here, doing the research, learning the real numbers, that tells me you’re already the kind of person who cares deeply about your partner’s wellbeing. That counts for a lot more than a virus ever could.

Want more support? Download our free e-book and handouts for a printable version of these stats you can share with a partner. Or if you want one-on-one help with disclosure, dating, and everything in between, check out coaching.

Frequently asked questions

What are the chances of getting herpes from one encounter?+
The per-act risk of getting genital herpes (HSV-2) from a single sexual encounter is low but not zero. Without condoms or antivirals, the risk is roughly 0.3% per act for male-to-female transmission and lower for female-to-male. With daily antivirals and consistent condom use, the annual risk in discordant couples drops to about 1-2%.
What is the HSV-2 transmission rate female to male?+
Female-to-male transmission of HSV-2 is significantly lower than the reverse. The annual rate in discordant couples is approximately 4% (compared to 8-10% for male-to-female). Per-act risk is roughly 0.04-0.10%. Condoms are about 65% effective in this direction, and daily antivirals cut risk by another 48%.
Can you get herpes with a condom?+
Yes, but condoms significantly reduce the risk. A pooled analysis found consistent condom use reduces HSV-2 acquisition by about 30% overall. Condoms are especially effective for protecting women (up to 96% reduction from male-to-female transmission). The reason condoms don't eliminate the risk entirely is that herpes spreads through skin-to-skin contact, and condoms don't cover all potentially affected areas.

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